用增材技术制造制药:工业4.0整合的关键驱动力
1Department of Pharmacy, Shri Ram Murti Smarak College of Engineering and Technology (Pharmacy), India.
Recent advances in drug delivery and formulation
|March 6, 2025
概括
增材制造 (三维打印) 通过个性化药物和可控的药物输送,彻底改变了药品行业. 关键的挑战包括材料,法规和效率,但未来的研究可以优化流程,以改善患者护理.
科学领域:
- 制药科学 制药科学
- 制造业 制造技术 制造技术
- 工业4.0 工业4.0 工业4.0 工业4.0 工业4.0 是什么?
背景情况:
- 增材制造 (AM) 是工业4.0的一个关键技术.
- 3D打印 (3DP) 能够实现新的制药应用.
研究的目的:
- 审查3D打印在创建个性化剂型和可控药物递送系统方面的能力.
- 确定制药行业中AM采用的挑战和机会.
- 分析AM与工业4.0原则的整合,以优化制造业.
主要方法:
- 药品中增材制造技术的文献综述.
- 分析了AM和工业4.0支柱之间的相互关系.
- 确定挑战和未来的研究方向.
主要成果:
- 3DP促进了个性化医疗,精确的药物释放和定制的输送系统,改善了治疗结果.
- 增材增材优化了制造成本,缩短了生产时间,并最大限度地减少了浪费.
- 关键的挑战包括材料选择,监管合规和工艺效率.
结论:
- 在制药制造业中对辅助药物进行整合需要跨学科的合作.
- 未来的研究应该专注于克服监管障碍,开发医疗级材料,并通过计算模型和机器学习优化流程.
- 成功整合AM将增强个性化患者护理和治疗有效性.
相关概念视频
01:28Factors Influencing Drug Absorption: Pharmaceutical Parameters
112
Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
112
01:26Drug Administration and Therapy Phases: Overview
402
Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
402