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Updated: May 24, 2025

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MHC I类贩运信号通过使用人工抗原呈现细胞改善了细胞毒性T淋巴细胞的诱导

Kenta Sasaki1,2, Kenji Murata1, Tomoyuki Minowa1,3

  • 1Department of Pathology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, 060-8556, Japan.

Biochemistry and biophysics reports
|March 6, 2025
PubMed
概括

人工抗原呈现细胞 (aAPC) 通过信号-MHC I类贩运信号 (SP-MITD) 融合基因进行工程,显著增强细胞毒性T淋巴细胞 (CTL) 诱导. 这种新的方法改善了对已知和未知的抗原的T细胞刺激.

关键词:
人工抗原呈现细胞 (aAPC)红血球白血病细胞系K562 细胞系K562MHC I 类的贩运信号 (MITD)

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