职业史调查问卷用于职位编码和系统性自身免疫性类风湿性疾病中的暴露评估
Anne-Catherine Dens1, Hannelore Celen2, Stijn Michiels3
1Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
Rheumatology advances in practice
|March 6, 2025
概括
一个新的自我管理问卷有效地评估了职业史和可呼吸晶体二氧化 (RCS) 暴露,为自身免疫疾病研究提供了面试的经济有效替代方案.
科学领域:
- 环境流行病学环境流行病学
- 职业健康 职业健康 职业健康
- 类风湿病学 类风湿病学
背景情况:
- 系统性自身免疫性类风湿性疾病 (SARDs) 与遗传易感性和环境因素,如可呼吸晶体二氧化 (RCS) 颗粒有关.
- 在以人口为基础的研究中评估职业暴露是至关重要的,但传统上是资源密集型的,通常需要专家采访.
研究的目的:
- 开发和验证一个自我管理的职业史问卷.
- 为了使1968年国际职业标准分类 (ISCO-68) 的编码和暴露评估.
- 为传统的职业暴露评估方法提供一个具有成本效益的替代方案.
主要方法:
- 70名类风湿性关节炎患者及其家属完成了电话采访和新的问卷.
- 独立观察员使用ISCO-68编码了工作,而工作暴露矩阵估计了RCS暴露.
- 根据工作年,ISCO-68代码和RCS暴露,使用科恩的 κ 和类内相关性评估了协议.
主要成果:
- 患者反应率为77%;对照反应率很低 (6.45%).
- 报告工作年份的高一致性 (91%) 和永远/从未RCS暴露的实质性一致性 (科恩的 κ = 0.87) 发现.
- 手动ISCO编码带来了变化,但对工作编码的观察者间可靠性很高 (ICC = 0.91).
结论:
- 自主管理问卷是一个有效的,具有成本效益和时间效率的工具,用于流行病学研究中的职业史和RCS暴露评估.
- 未来的研究应该集中在自动编码系统和改进的招聘控制策略上.
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