术内流体体积对胸部手术术后肺部并发症的影响:系统性审查和元分析
Shreya Das Adhikari1, Nitin Gupta2, Mukund Gupta3
1Department of Anaesthesiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
在胸部手术患者中,术后肺部并发症 (PPCs) 发生的术后肺部并发症 (PPCs) 的术内静脉输液 (IVF) 输注率更高. 限制性流体策略可能会减少PPC,但需要更多的研究.
科学领域:
- 麻醉学 麻醉学
- 关键护理医学 关键护理医学
- 胸部外科手术 胸部外科手术
背景情况:
- 胸部外科手术中缺乏清晰的流体管理指南.
- 手术后肺部并发症 (PPC) 是一个严重的问题.
- 术内流体策略可能会影响PPC的发展.
研究的目的:
- 为了比较手术内静脉输液 (IVF) 输注在有和没有PPC的患者.
- 评估流动策略 (限制性与自由) 与PPC之间的关联.
主要方法:
- 对比限制性和自由流体治疗的研究进行系统审查和元分析.
- 包括比较PPC和没有PPC患者的试管婴儿的研究.
- 在试管婴儿和PPCs的聚合风险比率中聚合平均差异的计算.
主要成果:
- 在元分析中包含了11篇文章.
- 在患有PPC的患者中,试管婴儿的平均值显著更高 (平均差异:1.51毫升/公斤/小时,P = 0.001).
- 在自由流体臂 (RR = 0.58;P = 0.06) 中,PPC的聚合比例较高,异质性较高.
结论:
- 增加的手术内试管婴儿与更高的PPC率有关.
- 限制性流体策略可能更安全,以减少胸部外科手术中的PPC.
- 由于研究的局限性,需要进一步进行高质量的随机对照试验.
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