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Updated: May 24, 2025

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在小鼠过敏喘模型中,HMOS 2'FL和3FL可以防止室内灰尘诱导的炎症性细胞因子释放in vitro,并降低小鼠过敏喘模型中的特定IgE产生

Marit Zuurveld1, Janna W M de Kleer1, Alinda J Berends1

  • 1Division of Pharmacology, Faculty of Science, Utrecht Institute for Pharmaceutical Science, Utrecht University, Utrecht, Netherlands.

Frontiers in nutrition
|March 6, 2025
PubMed
概括

人类牛奶寡糖 (HMOS),特别是2'-富可酸乳糖 (2'FL) 和3-富可酸乳糖 (3FL),显示出预防过敏喘的潜力. 这些化合物在实验室中调节了免疫反应,并在小鼠模型中降低了特定的IgE,尽管没有预防呼吸道炎症.

关键词:
先进的体外模型在体外模型中.过敏性喘 过敏性喘预防过敏 预防过敏人类牛奶中的寡糖类.粘膜的炎症 粘膜的炎症

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