身体圆度指数与中年和老年人认知障碍之间的关系:基于人口的横截面研究
Dandan Guo1, Tao Li2, Qingchao Yang1
1Department of Neurology, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Frontiers in aging neuroscience
|March 6, 2025
概括
身体圆度指数 (BRI) 可能预测认知障碍,特别是在年轻人中. 较低的BRI与中国研究中的认知衰退风险降低有关,这表明其有早期检测的潜力.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 认知障碍是一个重要的公共卫生问题,特别是在老年人群中.
- 肥胖与认知能力下降有关,但身体圆度指数 (BRI) 的作用尚不清楚.
- 了解BRI与认知障碍的关联对于风险人群至关重要.
研究的目的:
- 评估身体圆度指数 (BRI) 与认知障碍之间的关联.
- 为了确定BRI是否可以独立预测认知衰退.
- 研究一带一路的预测价值在农村,低收入,低教育的中国人群中.
主要方法:
- 在中国天津农村,对35-95岁的人进行横截面研究.
- 通过迷你精神状态检查 (MMSE) 评估认知功能;BRI计算和分类.
- 多变量后勤回归和子组分析探索了BRI与认知障碍的关系,考虑到年龄,性别和高血压.
主要成果:
- 36.5%的参与者患有认知障碍.
- 与第一个相比,BRI的第二个四分位数显示认知障碍风险比第一个低31% (OR:0.69).
- 在65岁以下的人群中,BRI与认知障碍有显著的关联,具有反转的U形剂量反应曲线.
结论:
- 除了年龄,性别和高血压,BRI还可以预测认知障碍,特别是在年轻人中.
- 使用BRI早期风险识别可能使认知衰退的及时干预成为可能.
- BRI提供了一种潜在的工具,可以减轻认知能力下降对个人和医疗保健系统的负担.
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