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Updated: May 24, 2025

siRNA Electroporation to Modulate Autophagy in Herpes Simplex Virus Type 1-Infected Monocyte-Derived Dendritic Cells
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HSV-1 UL56蛋白招募细胞NEDD4家族的泛素酶,以抑制CD1d表达和NKT细胞功能

Lingxi Qiu1, Xuedi Gao1, Xinyue Shao1

  • 1Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Journal of virology
|March 6, 2025
PubMed
概括

简单疹病毒1 (HSV-1) 使用UL56基因通过降解CD1d来逃避免疫系统,这抑制了自然杀手T (NKT) 细胞的功能. 这种机制对于HSV-1的发病和小鼠的毒性至关重要.

关键词:
CD1d 是一个CD1d.在 NKT NKT 中.在Nedd4LL中使用.在 UL56 UL56 的情况下.疹病毒 疹病毒免疫逃避 免疫逃避病毒病原体的病毒病原体.

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