全球流行病学,病毒进化和公共卫生反应:对Mpox (1958-2024) 的系统性审查
Vivekanand Jadhav1, Arundhuti Paul2, Vivek Trivedi1
1Department of Microbiology, Pacific Medical College and Hospital, Pacific Medical University, Bhilonka Bedla, Sukher, Udaipur, Rajasthan, India.
Journal of global health
|March 6, 2025
概括
麻疹 (Mpox) 从非洲地区性疾病演变为全球性健康问题. 最近的疫情凸显了加强监测和国际合作的必要性,以控制其传播.
科学领域:
- 流行病学 流行病学
- 病毒学 病毒学
- 公共卫生 公共卫生
背景情况:
- 麻疹 (Mpox) 是由Mpox病毒 (MPOXV) 引起的动物性病毒性疾病,首次在1958年被发现.
- 历来是中非和西非的特有病,Mpox已经显示出越来越大的国际传播潜力.
- 最近的全球疫情凸显了了解Mpox进化的必要性.
研究的目的:
- 从1958年到2024年系统评估Mpox的流行病学和病毒演变.
- 分析公共卫生对Mopox疫情的反应.
- 确定影响Mopox传输和管理的关键因素.
主要方法:
- 全球卫生报告,监测数据和科学文献的系统审查.
- 分析主要的Mpox疫情,传播模式和地理分布.
- 评估公共卫生干预措施,病毒突变和疫苗接种疗效.
主要成果:
- 2022年Mpox疫情被宣布为国际关注的公共卫生紧急情况,到2024年7月,全球报告了超过102,000例病例.
- 确定了两种不同的分类,I (中非) 和II (西非),Clade II推动了国际传播.
- 接种天花疫苗显示有保护作用,而人与动物的互动和国际旅行是新出现的危险因素.
结论:
- 马普克斯已经从一个区域性动物性传染病转变为一个重要的全球公共卫生挑战.
- 加强监测,国际合作和有针对性的干预措施对于缓解未来的Mpox疫情至关重要.
- 了解正在进行的流行病学转变对于有效的Mpox管理至关重要.
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