较高的饮食葡萄糖指数,但不是葡萄糖负荷,与性结肠炎的风险增加有关:一项前性队列研究
Shuyu Ye1, Tian Fu2,3, Yiwen Tu4
1Department of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha, China.
高饮食葡萄糖指数,而不是葡萄糖负荷,与性结肠炎 (UC) 风险增加有关. 降低血糖指数的食物可能会降低UC风险,突出其在饮食建议中的重要性.
科学领域:
- 营养科学 营养科学
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 总碳水化合物摄入量与炎症性肠病 (IBD) 风险之间存在不一致的关联.
- 葡萄糖指数 (GI) 和葡萄糖负荷 (GL) 是碳水化合物质量和数量的关键指标.
研究的目的:
- 调查饮食中的GI和GL与IBD亚型,特别是克罗恩病 (CD) 和性结肠炎 (UC) 的风险之间的关联.
主要方法:
- 利用了121,148名英国生物库参与者在基线没有IBD的数据.
- 使用经过验证的基于网络的24小时回忆问卷评估饮食摄入量.
- 采用了考克斯的比例危险模型和替代分析来评估关联.
主要成果:
- 较高的饮食GI与UC风险增加有关 (HR每1SD增量1.13;最高与最低四分位数1.46).
- 用低GI替代品取代中等或高GI食品与降低UC风险相关联.
- 在饮食GL和CD或UC风险之间没有发现显著的关联.
结论:
- 饮食葡萄糖指数,而不是葡萄糖负载,与性结肠炎的风险增加有关.
- 强调在UC的预防策略和建议中考虑饮食GI的重要性.
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