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相关概念视频

Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

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Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
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Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

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Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
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Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
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相关实验视频

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Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging
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基于领域知识的A型大动脉剖析的综合细分与临床导向的评估.

Shanshan Song1, Hailong Qiu2, Meiping Huang3

  • 1Department of Electronic and Computer Engineering, The Hong Kong University of Science and Technology, Hong Kong.

Medical image analysis
|March 6, 2025
PubMed
概括

甲型大动脉解剖 (TAAD) 需要快速诊断. 我们介绍了imageTAAD,一个数据集和SegTAAD方法用于自动细分,改善临床评估以获得更好的患者结果.

关键词:
一个基准的基准.临床导向的评估域名 知识 域名 知识医疗图像细分 医疗图像细分甲型大动脉剖析 (A型)

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科学领域:

  • 心血管成像 - 心血管成像
  • 医学图像分析 医学图像分析
  • 计算病理学计算病理学

背景情况:

  • 甲型大动脉剖析 (TAAD) 是一种关键的心脏紧急情况,需要快速诊断,预后预测和为患者的生存进行手术规划.
  • 与TAAD相关的解剖结构的手动细分具有挑战性,并且由于疾病的紧迫性和专业知识要求,在临床实践中不经常进行.
  • 现有的TAAD自动细分方法由于缺乏全面的公共数据集和临床导向的评估指标而受到限制.

研究的目的:

  • 通过引入 imageTAAD 来解决当前TAAD 研究的局限性,这是第一个具有临床导向评估的全面细分数据集.
  • 开发和验证SegTAAD,这是一个基础方法,用于全面的TAAD细分,其中包含域知识.
  • 为推进TAAD研究提供公开可用的数据集,代码和训练模型.

主要方法:

  • 创建图像TAAD,数据集包括120个由医学专家注释的病例,其中有35个前景类与TAAD诊断,预后和手术规划相关.
  • 确定四个关键的临床特征,以临床为导向的TAAD细分的评估.
  • 开发SegTAAD,一个细分方法,利用领域知识,了解边界的重要性和相对于TL和FL的撕裂位置.

主要成果:

  • 在图像TAAD数据集上,SegTAAD实现了最先进的 (SOTA) 性能,在整体DSC得分,95%的豪斯多夫距离和四个临床特征上优于其他方法.
  • 实验结果表明,SegTAAD有效地利用域名知识来提高细分精度.
  • 一个关键的发现是,较高的子相似系数 (DSC) 得分并不总是与临床特征提取的准确性有所相关.

结论:

  • 图像TAAD数据集和SegTAAD方法代表了A型大动脉剖析自动细分的重大进展.
  • 拟议的临床导向评估提供了更相关的对临床实用性细分性能的评估.
  • 该研究强调了将领域知识整合到细分模型中的重要性,并建议进一步研究细分指标和临床特征准确性之间的关系.