时间岛类型的时间加患者与不同的术后发作结果有不同的脑血流模式
Yuanfang Jiang1, Guixian Tang1, Shixin Liu2
1Department of Nuclear Medicine, PET/CT-MRI Center, Center of Cyclotron and PET Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510632, China.
Epilepsy & behavior : E&B
|March 6, 2025
概括
术前动脉旋转标记MRI在岛患者中揭示了明显的脑血流 (CBF) 模式. 没有扣押的结果与区域CBF变化相关,而没有扣押的结果显示了更广泛的网络中断.
科学领域:
- 神经成像是一种神经成像.
- 的研究研究.
- 大脑血液流动分析
背景情况:
- 时间加 (TPE),特别是时间岛型 (TI-TPE),带来了诊断挑战.
- 使用动脉旋转标记 (ASL) MRI 对脑血流 (CBF) 的术前评估对于预测TI-TPE手术结果至关重要.
研究的目的:
- 根据手术结果调查TI-TPE患者的手术前CBF差异.
- 分析与手术后的控制相关的voxel级和网络级CBF变化.
主要方法:
- 48名TI-TPE患者的回顾性分析由SEEG证实.
- 分类为没有发作 (SF,Engel IA) 和没有发作 (NSF,Engel IB-IV) 的组.
- 使用SPM和图形理论分析的3D-ASL数据,与健康对照 (HC) 相比.
主要成果:
- 在SF和NSF组中,在ipsilateral TTG/insula和contralateral MCG/precuneus中表现出降低的CBF,在ipsilateral STG/STP中增加的CBF.
- SF组表现出更明显的逆侧MCG/precuneushyperfusion和独特的逆侧STG/insulahyperfusion和calcarinehyperfusion. 这两种特征都比较明显.
- 与SF和HC组相比,NSF组显示显著破坏网络属性 (较高的Cp,Eglob,Eloc,Lp) 和更多异常节点.
结论:
- 在TI-TPE患者中,无论手术结果如何,都会显示出明显的voxel级和网络级CBF异常.
- 在没有扣押的组中,区域CBF变化更为突出,而在没有扣押的组中,网络中断更为广泛.
- 这些不同的模式可以预测手术后的发作结果.
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