使用QRS-VHis 基于间隔的算法来优化流出通道早发性心室综合体的废除过程
Linlin Wang1, Lei Wang2, Hailei Liu2
1Division of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China; Department of Cardiology, the Fourth Affiliated Hospital of Soochow University, Suzhou, China.
The Canadian journal of cardiology
|March 6, 2025
概括
QRS-VHis间隔准确地区分了左捆分支块 (LBBB) 类型的出流通道早发性心室综合体 (OT-PVC) 的左侧和右侧起源. 这个间隔通过可靠地指导导导管放置,优化了切除程序.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 确定流出通道过早心室复合体 (OT-PVCs) 的起源对于成功的切除至关重要.
- 左束枝分支块 (LBBB) 类型的OT-PVC在区分左心室和右心室起源方面存在挑战.
研究的目的:
- 评估QRS-VHis间隔在区分LBBB型OT-PVC的左心室和右心室起源方面的有效性.
- 开发和验证使用QRS-VHis间隔的算法,以优化除部位的选择.
主要方法:
- 在LBBB型OT-PVC患者中测量了QRS-VHis间隔.
- 将间隔的诊断性能与传统心电图 (ECG) 算法进行比较.
- 在多个中心开发并前性验证了基于流程图的算法.
主要成果:
- 在QRS-VHis间隔显示高精度 (AUC=0.962) 在区分起源,超越ECG算法.
- 一个QRS-V他的30毫秒的切线显示了71.8%的灵敏度和98.2%的特异性对左侧的起源.
- 开发的算法准确预测了需要左侧切除的需要,达到88%的成功率.
结论:
- QRS-VHis间隔是区分左心室和右心室外流通道起源在LBBB型OT-PVC中的一个高级度量.
- 这段时间间隔有助于优化手术内切除策略.
相关概念视频
Detection of Gross Error: The Q Test
5.1K
When one or more data points appear far from the rest of the data, there is a need to determine whether they are outliers and whether they should be eliminated from the data set to ensure an accurate representation of the measured value. In many cases, outliers arise from gross errors (or human errors) and do not accurately reflect the underlying phenomenon. In some cases, however, these apparent outliers reflect true phenomenological differences. In these cases, we can use statistical methods...
5.1K
Cochran's Q Test
180
Cochran's Q Test is a nonparametric statistical test used to determine if there are potential differences in the outcomes of three or more related groups on a binary (yes/no) or dichotomous outcome. It is essentially an extension of the McNemar Test, which is limited to two related samples - Cochran's Q test can handle three or more related samples, making it more versatile in scenarios where subjects are measured under multiple conditions. The test statistic follows a Chi-Square...
180
Real Time RT-PCR
56.7K
Real-time reverse transcription-polymerase chain reaction, or Real-time RT-PCR, is an analytical tool used to determine the expression level of target genes. The method involves converting mRNA to complementary DNA with the help of an enzyme known as reverse transcriptase, followed by the PCR amplification of the cDNA. These two processes can be performed simultaneously in a single tube or separately as a two-step reaction.
The real-time quantification of the number of amplified products is...
The real-time quantification of the number of amplified products is...
56.7K
2D NMR: Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC)
612
Heteronuclear single-quantum correlation spectroscopy (HSQC) is a 2D NMR technique that reveals one-bond correlations between hydrogen and a heteronucleus. The HSQC experiment is similar to the heteronuclear correlation experiment (HETCOR) but is more sensitive. In the HSQC spectrum, the proton chemical shift is plotted on the horizontal F2 axis, while the 13C chemical shift is plotted on the vertical F1 axis. The corresponding proton and 13C spectra are also shown. The HSQC contour plot does...
612
Radiological Investigation II: MRI and Ventilation Perfusion Scan
93
Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
93
Quartile
4.0K
Quartiles are numbers that separate the data into quarters. Quartiles may or may not be part of the data. To find the quartiles, first, find the median or second quartile. The first quartile, Q1, is the middle value of the lower half of the data, and the third quartile, Q3, is the middle value, or median, of the upper half of the data. To get the idea, consider the same data set:
1; 1; 2; 2; 4; 6; 6.8; 7.2; 8; 8.3; 9; 10; 10; 11.5
The median or second quartile is seven. The lower half of the...
1; 1; 2; 2; 4; 6; 6.8; 7.2; 8; 8.3; 9; 10; 10; 11.5
The median or second quartile is seven. The lower half of the...
4.0K


