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Updated: May 24, 2025

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针对PI3K/AKT/mTOR途径用于乳腺癌治疗的战略进展

Pankaj Garg1, Sravani Ramisetty2, Meera Nair3

  • 1Department of Chemistry, GLA University, Mathura, Uttar Pradesh 281406, India.

Biochemical pharmacology
|March 6, 2025
PubMed
概括

针对PI3K/AKT/mTOR通路对于晚期乳腺癌 (BC) 治疗至关重要. 本综述详细介绍了途径失调,当前的抑制剂和未来的策略,如免疫疗法,以改善患者的治疗结果.

关键词:
乳腺癌是什么? 乳腺癌是什么药物耐药性机制 抗药性机制在PI3K/AKT/mTOR路径中.发生PIK3CA突变的突变.在PTEN损失.途径抑制剂 途径抑制剂

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