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Updated: May 24, 2025

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
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利用蛋白质语言模型进行强大的抗微生物检测.

Lichao Zhang1, Shuwen Xiong2, Lei Xu3

  • 1School of Intelligent Manufacturing and Equipment, Shenzhen Institute of Information Technology, Shenzhen 518172, China.

Methods (San Diego, Calif.)
|March 6, 2025
PubMed
概括

这项研究介绍了PLAPD,这是一个新的深度学习框架,用于预测抗微生物 (AMP). PLAPD提供了一种更快,更准确的方法来发现新型AMP来对抗抗生素耐药性.

关键词:
抗微生物是一种抗微生物.深度学习是一种深度学习.蛋白质语言模型的模型变压器变压器变压器

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Leaky Scanning02:28

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
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