泰国女孩早期青春期的临床和流行病学见解:为期5年的研究
Phattariya Yaisilp1, Nattakarn Numsriskulrat2,3, Taninee Sahakitrungruang1,3
1Department of Pediatrics, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Annals of pediatric endocrinology & metabolism
|March 6, 2025
概括
早期青春期的评估在泰国女孩中越来越多,中部早期青春期是最常见的. 肥胖影响青春期的时间,需要体重管理和更新的医疗保健指南.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 生殖健康 生殖健康
- 公共卫生 公共卫生
背景情况:
- 全球各地都对女孩更早进入青春期表示担忧.
- 泰国女孩早发性和正常变异性青春期的流行数据有限.
- 这项研究解决了了解泰国早期青春期趋势的需要.
研究的目的:
- 研究泰国女孩早期青春期的患病率,特征和治疗方法.
- 分析2018年至2022年早期青春期评估的趋势.
- 在这个群体中确定影响青春期时间的因素.
主要方法:
- 对583名被评估为早期青春期的女孩的医疗记录进行了回顾性审查.
- 人口和临床特征的分析.
- 对各种形式的早期青春期治疗方法的评估.
主要成果:
- 观察到早期青春期评估的每年显著增加 (P=0.04).
- 依赖性激素释放激素 (GnRH) 的中央早发性青春期 (CPP) 占大多数 (71.2%) 的病例.
- 正常变异性青春期包括早期的正常青春期 (10.5%),过早的thelarche (9.5%),缓慢进展的早期青春期 (6.6%),和过早的上腺 (2.2%).
- 与缓慢进展的早熟青春期相比,患有CPP的女孩的BMIz分数和基底LH/FSH水平较高.
结论:
- 肥胖是影响泰国女孩青春期时间的一个重要因素.
- 需要预防性体重管理策略.
- 管理早期青春期的国家指南需要更新.
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