高频电磁辐射对暴露细菌中的细菌生存和抗生素活性的影响
Ehab A Hegazy1, May A El-Antrawy2,3
1Basic Science Department, Delta University for Science and Technology, Gamasa, 11152, Egypt.
Scientific reports
|March 6, 2025
概括
在特定频率的高频电磁波 (HFEMWs),如53 GHz,可以重新敏感抗生素耐药的细菌,如大肠杆菌和金黄色杆菌. 这表明HFEMW可以成为一种新的感染控制工具.
科学领域:
- * 微生物学 微生物学
- * 生物物理 生物物理
- * 电磁学 是一个电磁学领域.
背景情况:
- *高频电磁波 (HFEMWs) 可以影响细胞功能,影响细菌生长和抗生素敏感性.
- *了解这些相互作用对于开发新型抗菌药物策略至关重要.
- *大肠杆菌和黄金葡萄球菌是常见的细菌病原体,具有重要的临床意义.
研究的目的:
- * 调查HFEMW在广泛频段 (900 MHz至73 GHz) 对细菌活力和抗生素敏感性的影响.
- * 确定改变细菌对常见抗生素敏感性的特定频率.
- * 评估HFEMWs作为补充性抗菌方法的潜力.
主要方法:
- *对大肠杆菌和金黄色杆菌暴露于从900 MHz到73 GHz的HFEMW.
- *使用光学密度 (OD) 和殖民地形成单位 (CFU) 评估细菌生长.
- * 暴露后对抗生素 (ceftazidime,ceftaroline, gentamycin,doxycycline,ciprofloxacin) 的细菌敏感性的评估.
主要成果:
- *在51.8 GHz和53 GHz观察到显著的电磁干扰 (EMI) 影响,其中53 GHz的影响最为明显.
- *以前耐药的*E. coli*和*S. aureus*菌株在这些有效频率下对测试的抗生素表现出更高的敏感性.
- *70.6 GHz,73 GHz,900 MHz和1800 MHz频率对细菌活力或抗生素敏感性的影响有限或不显著.
结论:
- * HFEMWs对细菌活力和抗生素敏感性表现出频率依赖的影响.
- *特定的HFEMW频率可以克服关键细菌病原体的抗生素耐药性.
- * HFEMWs为感染控制和杀菌技术提供了一个有前途的补充策略,有可能减轻医院感染.
相关概念视频
Antibiotic Selection
52.1K
Overview
52.1K
Defense Against Bacterial Pathogens
1.4K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.4K
Biological Effects of Radiation
15.1K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
15.1K
The Electromagnetic Spectrum
52.4K
The electromagnetic spectrum consists of all the types of electromagnetic radiation arranged according to their frequency and wavelength. Each of the various colors of visible light has specific frequencies and wavelengths associated with them, and you can see that visible light makes up only a small portion of the electromagnetic spectrum. Because the technologies developed to work in various parts of the electromagnetic spectrum are different, for reasons of convenience and historical...
52.4K
Interaction of EM Radiation with Matter: Spectroscopy
1.4K
Electromagnetic (EM) radiation can be considered an oscillating electric and magnetic field propagating through a medium that can interact with matter in its path. The electric field in the radiation can interact with electrical charges in the atoms or molecules in the matter. On the other hand, the magnetic field can interact with the magnetic field in the atomic nucleus. The study of the interaction between electromagnetic radiation and matter is termed spectroscopy. Spectroscopy is the study...
1.4K
Bacterial Signaling
31.3K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
31.3K


