胎儿酒精谱系障碍 胎儿酒精谱系障碍
Riley J Felicicchia1, Christina R Veziris1, Sarah N Mattson2
1Department of Psychology, Center for Behavioral Teratology, San Diego State University, San Diego, CA, USA.
Current topics in behavioral neurosciences
|March 6, 2025
概括
产前酒精暴露 (PAE) 可以导致胎儿酒精谱系障碍 (FASDs),导致终身的身体和神经行为挑战. 早期干预对于管理这些发展影响至关重要.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 公共卫生 公共卫生
背景情况:
- 产前酒精暴露 (PAE) 会导致一系列的身体,神经行为和神经认知障碍.
- 这些障碍可以显著影响整个生命周期的发育轨迹.
- 胎儿酒精谱系障碍 (FASDs) 涵盖了因PAE而患有身体或神经行为障碍的个体所诊断的疾病.
研究的目的:
- 提供关于FASDs的当前知识的全面摘要.
- 涵盖诊断标准,神经行为结果,寿命考虑和FASDs可用的干预措施.
- 审查针对PAE影响的产前和产后干预的文献.
主要方法:
- 对FASDs当前知识的文献综述.
- 综合有关诊断标准和临床表现的信息.
- 审查关于神经发育结果和干预策略的研究.
主要成果:
- 患有PAE的人通常在执行功能,一般智力,运动技能,学习和记忆方面遇到挑战.
- 常见的相关问题包括侵略性,法律麻烦和反对行为.
- 神经发育的改变,如大脑体积减少和结构异常,是这些影响的基础,增加了同时出现疾病的风险.
结论:
- PAE导致FASDs的特征的一系列认知和行为缺陷.
- 对受PAE影响的人来说,考虑寿命和有针对性的干预措施是必不可少的.
- 对有效的产前和产后干预措施的进一步研究是有必要的,以减轻FASDs的长期影响.
更多相关视频
相关概念视频
Teratogenicity
2.3K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.3K
Autism Spectrum Disorder
53
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
53
Intellectual Disability
34
Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
34
CNS Depressants: Alcohol and Nicotine
166
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
166
Substance Use Disorders Affecting Sleep
152
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
152
Attention-Deficit/Hyperactivity Disorder
34
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
34


