在评估呼吸道疫苗非特异性影响的系统审查中使用半自动查工具的有效性
Charlie Holland1,2, Daniel B Oakes3,4, Mohinder Sarna3,5
1Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute Australia, Perth, WA, Australia. Charlie.holland@thekids.org.au.
BMC medical research methodology
|March 6, 2025
概括
研究选器 (RS) 是一个可靠的工具,准确识别系统审查的相关文章,显著减少选时间. 这种半自动化方法简化了研究,使系统审查更有效.
科学领域:
- 医学研究方法论医学研究方法论.
- 疫苗学 疫苗学 疫苗学
- 公共卫生 公共卫生
背景情况:
- 系统审查需要大量的研究人员时间来进行抽象选.
- 评估半自动化工具的效率对于大规模审查至关重要.
- 呼吸道疫苗对儿童健康的更广泛影响需要进行彻底的调查.
研究的目的:
- 为了确定研究选器 (RS) 的可靠性和有效性.
- 在对呼吸道疫苗的系统审查中评估RS的有效性.
- 评估RS对急性下呼吸道感染住院和抗菌素处方查效率的影响.
主要方法:
- 在 Medline,Embase,CINAHL,Scopus 和 ClinicalTrials.gov.gov 上进行了搜索.
- 包括人类对非特异性呼吸道疫苗影响的研究;不包括活体减弱疫苗.
- 通过RS对手工选进行选的摘要进行了比较,独立的审查员和冲突解决.
主要成果:
- 确定了9727件物品;3000件被随机选择进行选.
- RS确定了99个相关的物品,准确地捕获了它们.
- RS减少了选负载,只有4篇文章错过了 (2篇由于人为错误,2篇没有选).
结论:
- 研究选器是抽象选的一个有效和可靠的工具.
- 在大规模的系统性审查中,RS显著减少了时间负担.
- 建议使用RS来简化系统审查流程.
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