使用胃肠道面板评估腹患者的临床和微生物学概况,在一个高度复杂的中心
Jorge Andrés Salazar-Arenas1, Leidy Johanna Hurtado-Bermúdez2,3, Edgar David Salazar-Cardona2
1Departamento de Medicina Interna, Servicio de Gastroenterología, Fundación Valle del Lili, Cra 98 No. 18 - 49, Cali, 760032, Colombia.
BMC gastroenterology
|March 6, 2025
概括
胃肠道面板 (GIP) 有助于诊断成人腹,特别是在免疫功能低下的患者中. 这种诊断工具显著影响了治疗和康复,尽管访问仍然是一个挑战.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 胃肠道感染是一个全球性的健康问题,在哥伦比亚的发病率很高.
- 对于腹的传统诊断方法在灵敏度和特异性方面都有局限性.
- 胃肠道面板 (GIP) 可以快速检测多种病原体.
研究的目的:
- 描述哥伦比亚成人腹患者的临床和微生物特征.
- 评估GIP对免疫功能低下和免疫能力强的患者治疗的影响.
- 评估GIP在高度复杂的医院环境中的实用性.
主要方法:
- 一项从2021-2022年对350名成年患者进行的横截面观察研究.
- 对人口统计,临床,GIP发现和治疗数据的分析.
- 使用统计测试 (奇平方,费舍尔F,t测试,曼-惠特尼U) 进行免疫受损和免疫能力较强组的比较.
主要成果:
- 53%的GIP呈阳性,检测到多达5种病原体.
- 发现了细菌 (80%),病毒 (14.4%) 和寄生虫 (5.5%).
- 肠道病原性大肠杆菌,肠道聚合性大肠杆菌和C. difficile是最常见的细菌;诺罗病毒和Cryptosporidium分别是最常见的病毒和寄生虫.
- 在56.7%的患者中,GIP影响了治疗,导致90%的康复率.
结论:
- GIP是成人腹疾病的有价值的诊断工具,特别是在免疫受损的个体中.
- 标准化GIP标志是必要的,因为它的成本和有限的可访问性.
- 建议进一步研究GIP在当地环境中的成本效益.
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