超越泌尿动力学:在患有下泌尿道症状的男性中诊断脱体低活性的非侵入性方法 - 一项系统性审查
Karolina Garbas1, Łukasz Zapała2, Aleksander Ślusarczyk2
1Department of General, Oncological and Functional Urology, Medical University of Warsaw, Lindleya 4, 02-005, Warsaw, Poland. kgarbas98@gmail.com.
BMC urology
|March 6, 2025
概括
诸如DUA-SQ,超声波和AI之类的非侵入性方法显示,在患有LUTS的男性中,对诊断dtrusor underactivity (DU) 的可能性很大. 需要进一步的研究来提高它们在临床使用中的准确性和可靠性.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 诊断医学 诊断医学
- 医疗技术 医疗技术 医学技术
背景情况:
- 在男性中,下泌尿道症状 (LUTS) 是常见的.
- 阻断器低活性 (DU) 是LUTS的一个重要原因.
- 在男性中确切诊断DU可能具有挑战性.
研究的目的:
- 系统地审查和综合关于男性LUTS的DU非侵入性诊断方法的证据.
- 评估这些非侵入性方法的可行性和诊断准确性.
- 确定未来临床应用的有希望的诊断工具.
主要方法:
- 在PubMed,Scopus和Web of Science的系统文献搜索.
- 包括18项研究,包括7390名男性患者.
- 关于研究特征,诊断方法和准确性的数据提取;用于偏差评估的QUADAS-2.
主要成果:
- 评估的方法包括超声波,生物标志物,尿液流量计,问卷和人工智能模型.
- DUA-SQ问卷显示95.8%的灵敏度;超声波 (detrusor壁厚度) 的特异性为100%.
- 尿液流量测量和生物标志物显示出良好的灵敏度和特异性;人工智能模型显示出潜力.
- 显著的异质性和研究质量的局限性阻止了元分析.
结论:
- 像DUA-SQ,超声波和AI模型这样的非侵入性方法显示出诊断DU的潜力.
- 诊断准确性在方法之间有所不同,有些方法提供高灵敏度或特异性.
- 标准化和进一步的研究对于提高这些非侵入性诊断工具的可靠性至关重要.
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