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Updated: May 23, 2025

CRISPR-Mediated Reorganization of Chromatin Loop Structure
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染色体组织控制着癌症干细胞的转录反应和可塑性

Yinu Wang1, Jane Frederick2,3,4, Karla Isabel Medina2,3,4

  • 1Department of Obstetrics and Gynecology, Northwestern University, Chicago, IL, 60611, USA.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|March 7, 2025
PubMed
概括

癌症干细胞 (CSCs) 呈现出增加的纳米级染色体包装,增强它们的转录可塑性和对化疗的反应. 用药物向这些表观遗传领域可以逆转茎状性并促进分化.

关键词:
癌症干细胞是癌症干细胞.细胞的可塑性 细胞的可塑性染色体组织组织 染色体组织卵巢癌是发生在卵巢的癌症.转录的异质性转录的异质性

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