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Updated: May 23, 2025

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images
09:42

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images

Published on: September 7, 2017

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通过调制新合成的DNA链上的甲基化和延长表达,提高主要编辑效率

Xiaosong Han1,2, Xianghua Xu1, Youcai Xiong1

  • 1Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan, 430070, P. R. China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|March 7, 2025
PubMed
概括

研究人员发现,增加DNA甲基化提高了首席编辑器 (PE) 的效率. 他们开发了一种经期元素驱动的PE系统 (epiPE2),可以提高精确基因编辑,并允许在人类细胞中进行多重编辑.

关键词:
在EBNA1/oriP基因编辑 基因编辑甲基化处理的方法一个多重复合并的多重复合并.总编辑 总编辑 总编辑

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Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain13:11

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