心房的神经精神病学:痴呆症及其他疾病
Mayuresh Chaudhari1, Juan Rodriguez2, Alejandro Velasco2
1The Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Frontiers in cardiovascular medicine
|March 7, 2025
概括
心房动 (AF) 是一种常见的心律障碍,与痴呆症,焦虑症和情绪障碍有关. 有效地管理AF可以改善神经精神病的结果和患者的福祉.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 精神病学是一个精神病学.
背景情况:
- 心房动 (AF) 是全球最常见的心律障碍,影响1-2%的人口.
- AF与死亡率,发病率的显著增加以及痴呆症的更高风险有关.
- 除了认知能力下降之外,AF与焦虑和情绪障碍有关.
研究的目的:
- 审查关于心房动与神经精神疾病之间的关联的现有文献.
- 探索将AF与痴呆症,焦虑症和情绪障碍联系在一起的复杂机制.
- 讨论AF和并发性神经精神问题患者的潜在治疗策略.
主要方法:
- 对研究AF与神经精神疾病之间的关系的文献综述.
- 对拟议的病理生理机制的分析,将AF与痴呆症和情绪障碍联系起来.
- 关于AF和焦虑/情绪障碍的共享路径的证据综合.
主要成果:
- AF和痴呆症之间的关联涉及诸如中风,慢性大脑低 perfusion 和全身炎症等机制.
- 在AF和焦虑/情绪障碍之间存在双向关系,由共享的自主,神经内分泌和免疫系统功能障碍介导.
- 通过药理疗法优化AF管理,避免药物相互作用和行为干预措施显示出有希望.
结论:
- 心房 significantly 与痴呆,焦虑和情绪障碍的风险增加有关.
- 复杂的,多因素机制是AF和神经精神疾病之间的联系的基础.
- 对AF的综合管理策略可以积极影响相关的神经精神病并发症.
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