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Updated: May 23, 2025

An Assay for Quantifying Protein-RNA Binding in Bacteria
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An Assay for Quantifying Protein-RNA Binding in Bacteria

Published on: June 12, 2019

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对RsmA - mRNA相互作用的热力学建模捕获了在Pseudomonas aeruginosa转录组中的新型直接结合

Alexandra J Lukasiewicz1, Abigail N Leistra2, Lily Hoefner3

  • 1Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, United States.

Frontiers in molecular biosciences
|March 7, 2025
PubMed
概括

这项研究使用热力学建模预测了超过1000种Pseudomonas aeruginosa RsmA-mRNA相互作用,确定了457个涉及毒性和耐药性的新目标. 实验验证证证实了这些预测,扩大了我们对这种病原体的转录后调节的理解.

关键词:
伪omonas aeruginosa 这种类型的病毒.RNA的二级结构是RNA的二级结构.RNA结合蛋白质是RNA结合的蛋白质.RNA与蛋白质的相互作用计算建模计算建模转录后监管的规定.监管网络 监管网络是指监管网络.系统生物学 系统生物学

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