在查代谢的先天性错误的同时体质谱学:全面的书目测量分析
Victoria Kononets1, Gulmira Zharmakhanova1, Saule Balmagambetova2
1Department of Natural Sciences, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Frontiers in pediatrics
|March 7, 2025
概括
双重质谱法 (MS/MS) 是一种可靠的查代谢先天性错误 (IEM) 的方法. 这种文献计量分析绘制了研究格局,确定了IEM选的关键趋势和未来方向.
科学领域:
- 生物化学和分析化学的研究.
- 医学遗传学 医学遗传学
- 公共卫生和新生儿查
背景情况:
- 双重质谱法 (MS/MS) 是一种经过验证,道德和可靠的新生儿查方法.
- 代谢的先天性错误 (IEM) 涵盖了一系列需要早期检测的遗传疾病.
- 图书统计分析提供了科学成果和研究领域的合作的全面概述.
研究的目的:
- 为IEM查进行MS/MS研究的文献分析.
- 绘制科学界的网络结构 (国家,机构,作者,论文,关键词,来源).
- 从1991年到2024年5月,确定科学生产力,研究方向和合作努力.
主要方法:
- 使用PRISMA指南进行系统的文献搜索.
- 从科学网络核心集合 (WoSCC) 收集数据.
- 获取的文章的图书统计分析,重点是MS/MS用于IEM查.
主要成果:
- 分析了由3714名作者撰写的677篇文章,发表在245个期刊上,有21,193个引用.
- 确定了每篇文章的平均引用数为31.3个,H指数为69个.
- 揭示了关键的研究领域:选择性IEM查,新的治疗方法,MS/MS的新疾病,伦理考虑,新的查技术和与基因测序的整合.
结论:
- MS/MS是IEM查的基石技术,有着强大的和不断增长的研究机构.
- 该领域正在向更有针对性的查,先进的诊断和道德考虑方向发展.
- 未来的研究很可能会集中在将MS/MS与基因组学整合起来,并探索IEM检测和管理的新应用.
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