登杆中的肝生物转化 Anabas testudineus 暴露在环境相关度的聚烯微塑料中
Reeha Mashirin1, Kumari Chidambaran Chitra1
1Endocrinology and Toxicology Laboratory, Department of Zoology, University of Calicut, Kerala, India.
Journal of applied toxicology : JAT
|March 7, 2025
概括
聚烯微塑料 (PS-MPs) 危害水生生物,导致鱼类肝脏损伤和改变排毒. 即使在切除之后,肝脏组织的损伤仍然存在,这凸显了塑料污染带来的风险.
科学领域:
- 环境毒理学环境毒理学
- 水生生态毒理学 水生生态毒理学
- 生物标志物研究的研究.
背景情况:
- 聚烯微塑料 (PS-MPs) 是普遍存在的环境污染物.
- 水生生物因暴露于微塑料而面临越来越大的风险.
- 了解对鱼肝的毒理影响至关重要.
研究的目的:
- 调查暴露于PS-MPs的Anabas testudineus的肝脏生物转化和本病学变化.
- 评估环境相关的PS-MP度和暴露持续时间的影响.
- 评估经过净化期后影响的可逆性.
主要方法:
- 暴露在PS-MPs (13.6和23.6毫克/升) 的Anabas testudineus中长达60天.
- 监测解毒酶活动 (I期和II期) 和基因表达 (Cyp1a1,Ugt).
- 在暴露和净化后对肝脏组织进行了基因病理分析.
主要成果:
- 观察到显著诱导I期酶 (例如,EROD) 和改变II期酶活动.
- 持续性肝病变,亡,真空化和黑色素瘤细胞中心被注意到.
- 即使经过60天的净化期,组织病理损伤仍然明显.
结论:
- 阿纳巴斯testudineus对PS-MP暴露呈现适应性解毒反应.
- 在鱼类中,PS-MPs会导致严重和持续的肝损伤.
- 这些发现强调了水生环境中微塑料污染带来的生态风险.
相关概念视频
Types of Step-Growth Polymers: Polyesters
The introduction of polyesters has brought major development to the textile industry. The wrinkle-free behavior of polyester blends has eliminated the need for starching and ironing clothes.
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the polymer...
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the polymer...
Microbial Bioremediation of Hydrocarbons
Bioremediation is an environmentally sustainable process that employs living organisms—primarily microorganisms—to degrade or neutralize pollutants from contaminated environments. In oil spills and hydrocarbon pollution, bioremediation involves the use of hydrocarbon-degrading bacteria to transform toxic compounds into less harmful substances. This approach leverages natural microbial metabolic processes and is considered both cost-effective and ecologically favorable compared to physical or...
Bioplastics
Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...
Microbial Bioremediation of Plastics
Polyethylene terephthalate (PET) is a synthetic polymer widely utilized in the packaging industry, particularly for bottles and containers. Due to its chemical stability and durability, PET accumulates in the environment, contributing significantly to plastic pollution. It comprises repeating units of terephthalic acid and ethylene glycol, resulting in a semi-crystalline structure that is resistant to natural degradation processes.A notable breakthrough in plastic biodegradation came with the...


