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Updated: May 23, 2025

Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog
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Published on: November 5, 2014

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一个PDE4短形降解剂:第一个异型特异性的PDE4抑制

Donald H Maurice1

  • 1Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Canada.

The FEBS journal
|March 7, 2025
PubMed
概括

新的蛋白质分解向嵌合体 (PROTACs) 选择性降解特定化酶4 (PDE4) 的简称. 这种高度选择性的方法提供了对循环AMP (cAMP) 信号和炎症的强有力的控制.

关键词:
这是PDE4的.这就是PROTAC.cAMP - 信号传输系统基化酶是一种基化酶.

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