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Updated: May 23, 2025

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通过DRD2介导的AMPK化调节肝硬化发生的情况

Peng Ma1, Hao Ou1, Junze Cai1

  • 1School of Life Science and Technology, China Pharmaceutical University, Nanjing, Jiangsu, China.

Liver international : official journal of the International Association for the Study of the Liver
|March 7, 2025
PubMed
概括

多巴胺D2受体 (DRD2) 内部化通过破坏AKT-AMPK信号,使脂肪肝疾病 (MASH) 恶化. 一种DRD2抗剂,L-741626,通过阻断这种途径,显示出治疗MASH的潜力.

关键词:
D2多巴胺受体 (DRD2) 是一种现在的情况是:L-74162626腺5′-单酸盐 (AMP) 激活的蛋白激酶.代谢功能障碍相关的脂肪肝炎 (MASH)无处不在的化

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