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在绝经后妇女的骨和炎症标志物,身体组成和身体功能上,奎尔丁的疗效
Alyssa R Bailly1,2, Garrett M Hester3, Michaela G Alesi3,4
1Department of Exercise Science and Sport Management, Kennesaw State University, 520 Parliament Garden Way NW, Kennesaw, Georgia, 30144, United States of America. abailly24@unm.edu.
绝经后妇女补充奎尔素 (QUE) 有积极影响骨循环标志物,并减少炎症. 然而,它对骨吸收和长期骨保护的影响需要进一步研究.
科学领域:
- 营养科学 营养科学
- 骨生物学 骨生物学 骨生物学
- 免疫学 免疫学 免疫学
背景情况:
- 绝经后的女性经历了骨周转和炎症的变化.
- 昆素是一种植物性黄类物质,正在研究其潜在的健康益处.
- 绝经后,骨健康是一个重要的关注点.
研究的目的:
- 检查素补充剂对绝经后妇女骨循环标记物 (BTM) 和炎症标记物的90天影响.
- 评估奎尔素对骨矿物质密度 (BMD),身体组成和身体功能的影响.
- 评估奎尔塞丁在管理骨健康和炎症中的作用.
主要方法:
- 这是一项双盲,安慰剂控制的研究,涉及33名健康的绝经后妇女.
- 参与者每天接受500毫克奎尔 (QUE) 或甲基纤维素安慰剂 (PLB) 90天.
- 评估包括BTMs (OC,PINP,CTX),炎症标志物 (IL-6,TNF-α,CRP),BMD,身体组成和身体功能测试.
主要成果:
- 奎思补充剂显著增加骨形成标记物 (OC,PINP) 和骨再吸收标记物 (CTX).
- 与安慰剂相比,奎尔塞丁显著降低了促炎性细胞因子 (IL-6,TNF-α).
- 没有观察到CRP,身体组成或身体功能的显著变化.
结论:
- 奎尔素可以通过调节骨形成和减少炎症来帮助调节骨循环.
- 虽然奎尔提升了骨形成标记物,但骨再吸收标记物的增加需要进一步研究其骨保护作用.
- 需要进行更多的研究,才能充分了解奎尔丁在绝经后妇女的骨保护潜力.
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