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Updated: May 23, 2025

Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation
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Published on: March 21, 2020

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调节的配体赋予了帕金森病的风险,并影响了溶酶体

Hanwen Zhang1, Daniel Kargilis1, Thomas Tropea1

  • 1Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Annals of clinical and translational neurology
|March 7, 2025
PubMed
概括

帕金森病 (PD) 风险变体被选,以检测大脑脊髓液 (CSF) 对溶酶体功能的影响. 鉴定出CAMLG基因是一种神经元表达的风险基因,会影响 lysosomal 蛋白.

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