腹部脂肪与艾滋病毒感染者的身体功能有负面关联
Vitor Hf Oliveira1, Amanda L Willig2, Christine Horvat Davey3
1University of Washington, Seattle, WA.
AIDS (London, England)
|March 7, 2025
概括
增加的腹部脂肪与艾滋病毒感染者 (PWH) 的身体功能较差有关. 然而,较高的体力活动水平,包括中度至强度的体力活动 (MVPA) 和步数,可以改善身体功能,尽管腰围更大.
科学领域:
- 艾滋病毒/艾滋病研究研究
- 代谢健康 代谢健康
- 物理功能评估评估的物理功能评估.
背景情况:
- 艾滋病毒感染者 (PWH) 通常会经历身体组成的改变,包括增加腹部脂肪.
- 腹部脂肪和减少的身体功能是PWH在抗逆转录病毒治疗中的重大问题.
- 了解影响身体功能的因素对于管理PWH的长期健康至关重要.
研究的目的:
- 调查身体质量指数 (BMI),腹部脂肪和手握强度与PWH中的身体功能之间的关联.
- 探索身体活动和饮食质量如何改变这个人群中脂肪和身体功能之间的关系.
主要方法:
- 来自PROSPER-HIV研究的数据的横截面分析.
- 纳入标准:PWH接受抗逆转录病毒疗法,病毒载量<200副本/毫升.
- 测量:手握强度,短体能电池 (SPPB),体重指数,腰围,基于加速度计的体力活动,以及通过24小时召回的饮食质量.
主要成果:
- 在409名PWH中,71.4%的人超重/肥胖,72.4%的人腰围高.
- 在对年龄和性别进行控制后,在SPPB和腰围之间发现了负相关性 (P=0.02).
- 中度至强度的体力活动 (MVPA) 和步数显著影响了腰围-SPPB关系,较低的活动水平的负相关性更强.
结论:
- 增加的腹部脂肪与PWH中较差的身体功能有关.
- 高水平的MVPA和每日步骤与更好的身体功能有关,即使腰围升高.
- 身体活动干预措施可能有助于改善中部肥胖症PWH中的身体功能.
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