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Updated: May 23, 2025

Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays
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Published on: October 23, 2019

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基于结构的模拟的前性评估揭示了它们预测激酶突变对抑制剂结合的影响的能力

Sukrit Singh1, Vytautas Gapsys2, Matteo Aldeghi3

  • 1Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.

The journal of physical chemistry. B
|March 7, 2025
PubMed
概括

基于结构的计算方法可以准确预测影响癌症药物反应的激酶突变. 这项研究对这些方法进行了基准测试,为个性化医疗提供了一个工具,并预测癌症治疗中的耐药性.

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