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Updated: May 23, 2025

Induction and Testing of Hypoxia in Cell Culture
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缺氧诱导因子-1α驱动癌症对cuproptosis的抗性

Zhou Yang1, Wei Su2, Xiyi Wei3

  • 1Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.

Cancer cell
|March 7, 2025
PubMed
概括

缺氧诱导因子-1α (HIF-1α) 通过影响蛋白质脂解和铜代谢,在固体瘤中驱动对铜相关的细胞死亡 - - 铜亡的抗性. 抑制HIF-1α可以增加癌症对cuproptosis的敏感性.

关键词:
这就是cuproptosis.缺氧 缺氧是指缺氧的情况.缺氧诱导因子-1αα的诱导因子消化剂的消化方法是固体瘤是一种固体瘤.

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