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Updated: May 23, 2025

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
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Published on: December 3, 2020

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在物种之间基于生理学模型的甲基普雷迪尼索隆药理动力学,并将其推广到人类

Ruihong Yu1, William J Jusko1

  • 1Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, State University of New York at Buffalo, 160 Hayes Rd, Buffalo, NY 14214, United States.

Journal of pharmaceutical sciences
|March 7, 2025
PubMed
概括

这项研究开发了三种甲基prednisolone (MPL) 的全米生理学基础的药理动力学 (PBPK) 模型,以预测其跨物种的血度. 这些模型有助于更好地理解MPL在不同人群中的药理动力学.

关键词:
清除许可证的情况人类抽象推断.甲基普雷迪尼索隆 (Methylprednisolone) 是一种可以药理动力学 药理动力学种类扩大规模的变化

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