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溶解的有机物减轻了银纳米颗粒对淡水藻类的毒性:对氧化应激和膜功能的影响

Jilai Zhang¹, Chenglei Hu¹, Ming Jiang²

¹College of Resources and Environment, Yunnan Agricultural University, Kunming, 650201, People's Republic of China; Yunnan Engineering Research Center of Soil Fertility and Pollution Remediation, Kunming, 650201, People's Republic of China.

Environmental pollution (Barking, Essex : 1987)

|March 7, 2025

概括

溶解的酸 (DHA) 通过调节脂肪酸成分和减少氧化损伤,增强藻类生存,保护Chlorella vulgaris细胞膜免受银纳米粒子 (AgNPs) 和银离子 (Ag+) 的影响.

科学领域:

环境科学环境科学
生态毒理学生态毒理学
纳米技术纳米技术

背景情况:

银纳米粒子 (AgNP) 对水生生物细胞膜的毒性机制尚不清楚,特别是溶解有机物 (DOM).
银离子 (Ag+) 和AgNP是已知的对水生生物有毒物质,影响细胞膜完整性.
溶解的酸 (DHA) 是水生环境中常见的DOM成分.

研究的目的:

研究DHA对AgNP和Ag+对Chlorella vulgaris细胞膜的毒性的影响.
为了检查脂质过氧化,透性,脂肪酸概况,流动性和超结构的变化.
评估DHA对银诱导毒性的潜在细胞保护作用.

主要方法:

氏体暴露于AgNP和Ag+在DHA的缺席和存在下.
测量脂质过氧化,细胞膜透性和脂肪酸概况.
使用传输电子显微镜 (TEM) 分析膜流动性和超结构变化.

主要成果:

DHA促进了C. vulgaris的生长,增加了AgNP和Ag+的EC50值.
作为对银暴露的反应,DHA显著降低了脂质过氧化和脂肪酸组成的变化 (增加UFA,减少SFA).
DHA增强了膜流动性,并减少了由AgNP和Ag+引起的超结构损伤 (细胞质分解,真空化).

结论:

DHA在C. vulgaris细胞膜上表现出对AgNP和Ag+毒性的细胞保护作用.
DHA可能调节藻类细胞膜脂肪酸成分,有助于保持结构和功能完整性.
这些发现强调了DOM在减轻水生生态系统中纳米材料毒性的关键作用.

关键词:

菌 (Chlorella vulgaris) 是一种常见的植物.溶解的胺酸是什么?脂肪酸概况分析脂肪酸概况分析膜的特性膜的特性纳米毒性纳米毒性

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