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Updated: May 23, 2025

Detection of Mitochondria Membrane Potential to Study CLIC4 Knockdown-induced HN4 Cell Apoptosis In Vitro
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线粒体蛋白酶ClpP是治疗多发性骨髓瘤的有希望的目标

Xiang Liu1, Jinlong Gu2, Song Liu2

  • 1Department of Hematology/Institute of Hematology, West China Hospital, Sichuan University, Chengdu, China.

Biochemical pharmacology
|March 7, 2025
PubMed
概括

一种新型化合物,7b,向线粒体病原分解蛋白酶P (ClpP),有效地杀死多发性骨髓瘤 (MM) 细胞,包括耐药类型. 这种ClpP激活为复发性和耐火性MM提供了一个有前途的治疗策略.

关键词:
这就是为什么ClpPP.线粒体中的线粒体.多发性骨髓瘤是一种多发性骨髓瘤.氧化酸化是一种氧化酸化.

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