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在治疗慢性髓性白血病的阿斯基米尼布治疗期间怀孕双胞胎 - 一个病例报告

Géssika B G M Gutierrez de Moraes Pereira¹, Victor A Rocha¹, Paulo Victor R Barbosa¹

¹Centro de Hematologia e Hemoterapia (Hemocentro-UNICAMP), Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil.

Annals of hematology

|March 7, 2025

概括

本案例报告详细介绍了一名患有慢性髓性白血病 (CML) 的患者成功怀孕双胞胎,该患者此前对其他治疗方法有抗性. 该患者在怀孕早期接触过阿斯基米尼布,突出显示了对氨酸激酶抑制剂的安全性考虑.

科学领域:

血液学血液学血液学
在瘤学瘤学.
生殖医学生殖医学

背景情况:

在怀孕期间治疗慢性髓性白血病 (CML) 是具有挑战性的,因为有限的安全治疗选择.
大多数氨酸激酶抑制剂 (TKIs) 是致性的,特别是在头三个月,需要谨慎管理.
阿西米尼布是一种具有独特作用机制的全osteric TKI.

关键词:

亚斯基明尼比 (Asciminib) 是一种抗体.慢性骨髓性白血病慢性骨髓性白血病怀孕怀孕怀孕怀孕铁氨酸激酶抑制剂铁氨酸激酶抑制剂

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