西班牙骨矿物质密度状况的更新:OsteoSER研究
Carmen Gómez-Vaquero1, Marta Domínguez-Álvaro2, Daniel Seoane-Mato2
1Rheumatology Department, Hospital Universitari de Bellvitge, Carrer de La Feixa Llarga, S/N, 08907 L'Hospitalet de Llobregat, Barcelona, Spain. carmen.gomez@bellvitgehospital.cat.
Archives of osteoporosis
|March 7, 2025
概括
这项研究为西班牙人口提供了最新的骨矿物质密度 (BMD) 参考数据,揭示了体力活动可以提高峰值骨质量,而吸烟会损害骨质量. 骨质疏松症和骨质疏松症在50岁以上的成年人中普遍存在,尤其是女性.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 老年学是一门学科.
背景情况:
- 对于西班牙人口而言,已确定的骨矿物质密度 (BMD) 参考数据来源于1989年多中心骨质疏松症研究项目 (MRPO).
- 开始进行OsteoSER研究是为了更新这些关键的BMD参考数据,以适用于当代西班牙人口.
研究的目的:
- 为了确定20岁及以上的西班牙人腰椎,大腿部和全部的BMD分布.
- 为了比较更新的西班牙BMD数据与MRPO和美国国家健康和营养检查调查III (NHANES III) 的既定参考数据.
主要方法:
- 一项多中心,横截面的观察性研究,涉及1522名年龄在20-80岁的西班牙白人参与者.
- 参与者从城市和农村地区招募,根据性别,年龄和体重指数 (BMI) 分层选择.
- 使用Hologic® Horizon W密度计测量骨矿物质密度.
主要成果:
- 在所有测量的骨部位中,在20-39岁之间的两性观察到峰值骨质量.
- 骨质量显示与身高,BMI和体育活动有积极的关联,与吸烟有负面的关联.
- 在50岁及以上的成年人中,骨质疏松症影响了54.4%,骨质疏松症影响了10.7%,女性患病率更高,随着年龄的增长而增加.
结论:
- 来自OsteoSER研究的骨矿物质密度参考数据与之前的MRPO和NHANES III发现密切一致.
- 身体活动在达到峰值骨质量方面发挥着重要作用,而吸烟对骨健康产生不利影响.
- 该研究强调了西班牙50岁以上人口中骨质疏松症和骨质疏松症的高患病率,强调了针对性干预的必要性.
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