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Updated: May 23, 2025

Author Spotlight: Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator
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Author Spotlight: Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator

Published on: May 19, 2023

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一个肥胖的FTO等位基因导致人类骨肌细胞的加速发育,生长和胰岛素抵抗

Lu Guang1,2,3, Shilin Ma1,2,3, Ziyue Yao1,2,3

  • 1Key Laboratory of Organ Regeneration and Reconstruction, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.

Nature communications
|March 7, 2025
PubMed
概括

FTO基因变异rs9939609-A通过过度刺激胰岛素/IGF信号,加速肌肉衰老和胰岛素抵抗. 这一发现有助于解释FTO变体与瘦身和肥胖之间的矛盾联系.

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