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Updated: May 23, 2025

Uracil-DNA Glycosylase Assay by Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry Analysis
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Uracil-DNA Glycosylase Assay by Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry Analysis

Published on: April 22, 2022

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当 UDG 在 dsDNA 中识别出一个翻转出来的 uracil 基时的"非常时刻"

Vinnarasi Saravanan1, Nessim Raouraoua1, Guillaume Brysbaert1

  • 1University of Lille, CNRS, UMR8576, Unité de Glycobiologie Structurale et Fonctionnelle (UGSF), F-59000, Lille, France.

Scientific reports
|March 7, 2025
PubMed
概括

乌拉-DNA糖酶 (UDG) 可能通过涉及DNA机制的机制在DNA中识别乌拉基. 分子动力学模拟表明,机械力可以诱导基,促进UDG在染色质中结合.

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A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase111:25

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