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Updated: May 23, 2025

High Throughput In Vitro Assessment of Latency Reversing Agents on HIV Transcription and Splicing
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染色质对HIV-1潜伏期的影响:一个多维视角

Joanna E Jones1,2, Chelsea E Gunderson1,2, Brian Wigdahl1,2,3

  • 1Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, 19102, USA.

Epigenetics & chromatin
|March 7, 2025
PubMed
概括

人类免疫缺陷病毒1型 (HIV-1) 通过病毒前期DNA集成建立潜伏储存库. 染色体结构,包括2D和3D环境,关键调节HIV-1潜伏和重新激活,提供治疗点.

关键词:
3D染色质的三维染色体染色体重塑 染色体重塑 的方法艾滋病病毒-1 艾滋病病毒-1艾滋病毒-1 治愈 治愈 治愈延迟时间 延迟时间 延迟时间

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