阳性益生菌通过抑制氨酸和Hippo-YAP通路来改善乙氨基诱导的肝毒性

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Updated: May 23, 2025

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
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An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment

Published on: December 3, 2020

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Wenkang Gao1, Gang Wang2, Hang Yuan1

  • 1Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, Hubei, China.

Cell & bioscience
|March 7, 2025
PubMed
概括

一种由Bifidobacterium Longum,Streptococcus thermophilus和Lactobacillus delbrueckii亚种bulgaricus (BSL) 组成的益生菌混合物通过恢复肠道细菌和抑制肝损伤途径来改善乙氨基诱导的肝损伤 (AILI). 氨酸通过激活河马路径来加剧AILI.

关键词:
乙氨基是一种分支链氨基酸分支链氨基酸.失生症是一种失生症.我们的肠道微生物组.肠 - 肝轴 肠 - 肝轴益生菌 益生菌 益生菌

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