报告给美国中毒中心的非致命儿科芬太尼暴露,2015-2023年
Joseph J Palamar1, Linda B Cottler2, Joshua C Black3
1Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA.
The American journal of drug and alcohol abuse
|March 8, 2025
概括
从2015年到2023年,儿童芬太尼暴露率升了1000%以上,摄入是常见的. 超过三分之一的这些非致命的过量用药病例有严重的后果,突出了针对年轻人的预防需要.
科学领域:
- 毒理学 毒理学 毒理学
- 儿科健康 儿科健康
- 公共卫生 公共卫生
背景情况:
- 美国不断升级的阿片类药物危机越来越多地是由芬太尼驱动的.
- 在了解非致命的过量使用趋势及其对儿科病人的影响方面存在关键差距.
- 芬太尼的普遍威胁需要针对弱势年龄组进行专注的研究.
研究的目的:
- 为了确定非致命的儿科芬太尼暴露的流行率.
- 为了确定这些风险的相关特征.
- 确定这些特征与重大,危及生命的结果的相关性.
主要方法:
- 采用了一种重复的横截面研究设计.
- 收集了关于儿童非致命芬太尼暴露 (年龄0-19岁) 的数据,这些数据被报告给49个美国州的中毒控制中心.
- 研究期间从2015年到2023年.
主要成果:
- 报告共有3009例非致命的儿科芬太尼暴露.
- 在2015年至2023年期间,暴露率总体上大幅增加了1,194.2%,年轻人 (0-12岁) 和青少年 (13-19岁) 群体的显著增加.
- 摄入是主要的施用途径;小孩无意暴露占主导地位,青少年滥用则普遍存在. 41.0%的暴露导致重大,危及生命的效应.
结论:
- 儿科芬太尼暴露率正在迅速增加,构成严重的公共卫生威胁.
- 这些暴露中的很大一部分是无意的,或者导致严重的健康后果.
- 紧急,以年轻人为中心的预防和降低伤害的战略是必不可少的,特别是考虑到芬太尼含有的假冒药丸的扩散.
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