选择性并发症增加了结直肠癌查期间不完全结直肠镜检查的可能性
Camilla Thorndal1, Birgitte Skau2, Issam Al-Najami1,3
1Department of Surgery, Odense University Hospital, Svendborg, Denmark.
Scandinavian journal of gastroenterology
|March 8, 2025
概括
某些并发症显著增加了结肠直肠癌查期间不完整结肠镜检查的风险. 这些特定的健康状况可以作为结肠镜成功的预测因素.
科学领域:
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 不完整结肠镜检查率受人口因素和一般伴随疾病的影响.
- 有限的研究集中在特定的并发病对结肠镜检查完整性的影响上.
- 了解这些关联对于改善结肠直肠癌 (CRC) 查疗效至关重要.
研究的目的:
- 调查选定的并发病症与不完全结肠镜检查的可能性之间的关联.
- 确定可能预测CRC查参与者的结肠镜失败的特定并发症.
- 为优化危险人群结肠镜检查程序的策略提供信息.
主要方法:
- 一项基于登记的研究,涉及71,973名丹麦查参与者,在便免疫化学测试阳性后接受了结肠镜检查.
- 并发症被分为不同的组,包括血液,内分泌 (与糖尿病相关和非糖尿病),胃肠道,肝胆道和胰腺 (HBP),癌症和精神疾病.
- 采用多变量逻辑回归模型来分析并发症和不完整的结肠镜检查结果 (肠道准备不良或其他原因) 之间的关联.
主要成果:
- 7.5%的结肠镜检查是不完整的 (3.6%是由于肠道准备不良,3.9%是由于其他原因).
- 在几种并发症和不完整的结肠镜检查之间发现了显著的关联. 例如,与糖尿病相关的内分泌疾病的几率比 (OR) 为1.86因肠道不良准备和1.19因其他原因.
- 血液学疾病,HBP疾病和精神疾病也表明,由于肠道准备不佳,不完整结肠镜检查的几率增加.
结论:
- 特定的并发症与不完整结肠镜检查的更高概率显著相关.
- 这些已识别的并发症可以作为结肠镜成功的潜在预测因素.
- 针对性干预或对这些并发症患者的查方案的调整可以提高结肠镜完成率.
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