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Updated: May 23, 2025

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
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AKR1C3通过Nrf-2/NF-κB通路保护心肌细胞免受低氧诱导的细胞亡

Wenlu Zhang1, Wei Tian2, Xin Xia1

  • 1Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine. Shanghai 200025, China.

Acta biochimica et biophysica Sinica
|March 8, 2025
PubMed
概括

阿尔多降解酶1C3 (AKR1C3) 通过减少氧化应激和炎症,保护心脏细胞免受低氧 (低氧) 引起的损伤. 这一发现为急性心肌梗塞 (AMI) 和其他心脏病提供了新的治疗点.

关键词:
在 AKR1C3C3 中.在 NF-κBB 中.在 Nrf-2 中.心肌细胞亡 (cardiomyocyte apoptosis) 是一种导致心肌细胞亡的过程.缺氧 缺氧是指缺氧的情况.

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