患有心房动的狗的每日心率变化
Joao Escalda1, Brigite Pedro2,3,4,5, Jose Novo Matos1
1The Queen's Veterinary School Hospital, University of Cambridge, Cambridge, UK.
Journal of veterinary internal medicine
|March 8, 2025
概括
在接受抗失常药物 (AAD) 的心房动 (AF) 狗中,每日心率的变化是最小的. 单个24小时的霍尔特记录足以评估这些狗患者的速率控制.
科学领域:
- 兽医心脏病学 兽医心脏病学
- 狗类电生理学 狗类电生理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 用抗心律药物 (AAD) 治疗心房动 (AF) 的狗的每日心率变化尚未得到充分证实.
- 这种变化可能会影响关于治疗疗效的临床决策.
研究的目的:
- 为了评估每天平均心率 (meanHRHolter) 的一致性,在接受AAD的AF狗中.
- 为了评估连续24小时的霍尔特记录之间心室节律失常 (VAs) 的变化.
主要方法:
- 一项前性,描述性,多中心研究,涉及25只患有AF的狗.
- 分析了两个连续24小时的霍尔特记录,以比较HRHolter和VA的平均值.
- 使用布兰德-阿尔特曼分析和类内相关系数 (ICC) 来评估一致性.
主要成果:
- 非常小的偏差和高的ICC (0.98) 表明了记录之间平均HRHolter的良好一致.
- 在连续24小时期间的平均HRHolter中没有发现统计学意义上的差异.
- 只有8%的狗在平均HRHolter中显示出临床显著的变化,4%的狗有不同的速率控制分类.
结论:
- 在AAD上AF的狗中,每日心率的变化很低,这支持单个24小时的霍尔特记录对节奏控制评估的充分性.
- 然而,心室节律失常的每日变化在评估同期AF的狗中该参数时需要考虑.
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