通过远程分层和凝块残留物的磁化来快速去除血块
Qinglong Wang1,2, Ben Wang1, Kai Fung Chan3,4
1College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, China.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|March 8, 2025
概括
这项研究引入了一个微型机器人群,用于快速去除中风治疗中的血块,显著减少了手术时间和与长期缺氧和纳米粒子暴露相关的风险.
科学领域:
- 生物医学工程 生物医学工程
- 纳米技术 纳米技术
- 医疗机器人 医疗机器人
背景情况:
- 微/纳米机器人设备为静脉内疗法和向药物输送提供了精确度.
- 目前用于中风治疗的微型/纳米机器人方法需要漫长的程序,由于长时间的缺氧,有可能导致神经组织缩.
- 在机器人辅助血栓分析中需要更快,更安全的方法.
研究的目的:
- 开发一种可编程的合体微群,用于快速分离和去除血块.
- 为了实现快速的再通道化而没有完全的凝块降解.
- 为了最大限度地减少纳米颗粒的暴露,并减少二次凝血风险.
主要方法:
- 开发一个可编程的合体微群.
- 使用微群体从血管壁上分离血块.
- 使用分离的凝块碎片作为磁性"碎片机器人"通过螺旋式游泳进行推进.
- 使用导管吸管提取碎片的检索.
主要成果:
- 成功快速分离血栓. 血栓的成功快速分离.
- 有效的推进和回收凝血碎片.
- 完成整个过程,包括交付和取回,大约30分钟.
- 与中风治疗的关键"黄金6小时"相比,大大节省了时间.
结论:
- 开发的微群能够快速进行再通道,解决目前机器人辅助血栓溶解的局限性.
- 碎片机器人检索方法最大限度地减少了纳米颗粒暴露和二次凝固风险.
- 这种方法代表了机器人辅助中风治疗的重大进步,提供了更快,更安全的治疗选择.
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