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Updated: May 23, 2025

Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype
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Published on: June 17, 2022

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在多发性骨髓瘤中,Profilin 1通过自来降低CD138表达,从而诱导药物耐药性

Ya Wang1, ZiYu Dai2, Shengying Xiao3

  • 1Lung Cancer and Gastrointestinal Unit, Department of Medical Oncology, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha, 410013, China.

Discover oncology
|March 8, 2025
PubMed
概括

素1 (PFN1) 驱动多发性骨髓瘤 (MM) 中的博特佐米布耐药性,通过自来降低CD138的调节. 抑制自或过度表达CD138可以克服这种抵抗,提供新的治疗策略.

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