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Updated: May 23, 2025

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在癌症治疗中准dePARylation

Peng Li1, Duo Wu1, Xiaochun Yu1

  • 1Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China; School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China; Institute of Basic Medical Sciences, Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China.

DNA repair
|March 8, 2025
PubMed
概括

多分子ADP-ribosyl化 (PARylation) 是DNA修复的关键. 抑制像PARG这样的dePARylation酶对新型癌症疗法具有前景,与当前的PARP抑制剂不同.

关键词:
癌症治疗治疗 癌症治疗修复DNA损伤的修复脱巴利化 脱巴利化在巴黎的公园里这是一种PARylation.

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