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Updated: Jul 29, 2026

Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC Crosslinking of Small Molecules to Isolate Chromatin
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对克洛法拉宾与DNA的结合机制的深入研究:彻底的实验和理论调查

Soykan Agar1, Pelin Şenel1, Abdullah Al Faysal1

  • 1Department of Chemistry, Faculty of Arts and Sciences, Istanbul Technical University, Maslak, Istanbul 34469, Türkiye.

Computational biology and chemistry
|March 8, 2025
PubMed
概括

克洛法拉宾 (CLO) 通过微小的沟相互作用与鱼精子DNA (dsDNA) 结合,主要是由结合驱动的. 对CLO-DNA动态的理解对于药物开发和预测不良影响至关重要.

关键词:
克洛法拉宾 (Clofarabine) 是一种DsDNADNA是什么意思沟结合 沟结合 沟结合分子对接是分子对接.分子动力学分子动力学

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